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Synthesis and Different Effects of Biotinylated PAMAM G3 Dendrimer Substituted with Nimesulide in Human Normal Fibroblasts and Squamous Carcinoma Cells

Squamous cell carcinoma (SCC) remains a main cause of mortality in patients with neck and head cancers, with poor prognosis and increased prevalence despite of available therapies. Recent studies have identified a role of cyclooxygenases, particularly inducible isoform cyclooxygenase-2 (COX-2) and i...

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Detalles Bibliográficos
Autores principales: Uram, Łukasz, Filipowicz-Rachwał, Aleksandra, Misiorek, Maria, Winiarz, Aleksandra, Wałajtys-Rode, Elżbieta, Wołowiec, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770390/
https://www.ncbi.nlm.nih.gov/pubmed/31480608
http://dx.doi.org/10.3390/biom9090437