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Cell Heterogeneity and Phenotypic Plasticity in Metastasis Formation: The Case of Colon Cancer
The adenoma-to-carcinoma progression in colon cancer is driven by a sequential accumulation of genetic alterations at specific tumor suppressors and oncogenes. In contrast, the multistage route from the primary site to metastasis formation is underlined by phenotypic plasticity, i.e., the capacity o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770401/ https://www.ncbi.nlm.nih.gov/pubmed/31540068 http://dx.doi.org/10.3390/cancers11091368 |