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Cell Heterogeneity and Phenotypic Plasticity in Metastasis Formation: The Case of Colon Cancer

The adenoma-to-carcinoma progression in colon cancer is driven by a sequential accumulation of genetic alterations at specific tumor suppressors and oncogenes. In contrast, the multistage route from the primary site to metastasis formation is underlined by phenotypic plasticity, i.e., the capacity o...

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Detalles Bibliográficos
Autores principales: Teeuwssen, Miriam, Fodde, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770401/
https://www.ncbi.nlm.nih.gov/pubmed/31540068
http://dx.doi.org/10.3390/cancers11091368