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Influenza A Hemagglutinin Passage Bias Sites and Host Specificity Mutations

Animal studies aimed at understanding influenza virus mutations that change host specificity to adapt to replication in mammalian hosts are necessarily limited in sample numbers due to high cost and safety requirements. As a safe, higher-throughput alternative, we explore the possibility of using re...

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Detalles Bibliográficos
Autores principales: Lee, Raphael T. C., Chang, Hsiao-Han, Russell, Colin A., Lipsitch, Marc, Maurer-Stroh, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770435/
https://www.ncbi.nlm.nih.gov/pubmed/31443542
http://dx.doi.org/10.3390/cells8090958