Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity

The endocannabinoid system represents an integrated neuronal network involved in the control of several organisms’ functions, such as feeding behavior. A series of hybrids of 5-(4-chlorophenyl)-1-(2,4-dichloro-phenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide (mimonabant), a well-known i...

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Detalles Bibliográficos
Autores principales: Dimmito, Marilisa P., Stefanucci, Azzurra, Pieretti, Stefano, Minosi, Paola, Dvorácskó, Szabolcs, Tömböly, Csaba, Zengin, Gokhan, Mollica, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770484/
https://www.ncbi.nlm.nih.gov/pubmed/31527522
http://dx.doi.org/10.3390/biom9090492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770484/
https://www.ncbi.nlm.nih.gov/pubmed/31527522
http://dx.doi.org/10.3390/biom9090492

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