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Endoplasmic Reticulum Stress Increases DUSP5 Expression via PERK-CHOP Pathway, Leading to Hepatocyte Death

Hepatocyte death is critical for the pathogenesis of liver disease progression, which is closely associated with endoplasmic reticulum (ER) stress responses. However, the molecular basis for ER stress-mediated hepatocyte injury remains largely unknown. This study investigated the effect of ER stress...

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Detalles Bibliográficos
Autores principales: Jo, Hye Jin, Yang, Jin Won, Park, Ji Hye, Choi, Eul Sig, Lim, Chae-Seok, Lee, Seoul, Han, Chang Yeob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770509/
https://www.ncbi.nlm.nih.gov/pubmed/31491992
http://dx.doi.org/10.3390/ijms20184369