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A Super-Clustering Approach for Fully Automated Single Particle Picking in Cryo-EM

Structure determination of proteins and macromolecular complexes by single-particle cryo-electron microscopy (cryo-EM) is poised to revolutionize structural biology. An early challenging step in the cryo-EM pipeline is the detection and selection of particles from two-dimensional micrographs (partic...

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Detalles Bibliográficos
Autores principales: Al-Azzawi, Adil, Ouadou, Anes, Tanner, John J., Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770523/
https://www.ncbi.nlm.nih.gov/pubmed/31480377
http://dx.doi.org/10.3390/genes10090666