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A Super-Clustering Approach for Fully Automated Single Particle Picking in Cryo-EM
Structure determination of proteins and macromolecular complexes by single-particle cryo-electron microscopy (cryo-EM) is poised to revolutionize structural biology. An early challenging step in the cryo-EM pipeline is the detection and selection of particles from two-dimensional micrographs (partic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770523/ https://www.ncbi.nlm.nih.gov/pubmed/31480377 http://dx.doi.org/10.3390/genes10090666 |