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AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells

The renin–angiotensin receptor AT2R controls systemic blood pressure and is also suggested to modulate metastasis of cancer cells. However, in the latter case, the mechanisms involved downstream of AT2R remain to be defined. We recently described a novel Caveolin-1(CAV1)/Ras-related protein 5A (Rab5...

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Detalles Bibliográficos
Autores principales: Martínez-Meza, Samuel, Díaz, Jorge, Sandoval-Bórquez, Alejandra, Valenzuela-Valderrama, Manuel, Díaz-Valdivia, Natalia, Rojas-Celis, Victoria, Contreras, Pamela, Huilcaman, Ricardo, Ocaranza, María Paz, Chiong, Mario, Leyton, Lisette, Lavandero, Sergio, Quest, Andrew F.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770525/
https://www.ncbi.nlm.nih.gov/pubmed/31484460
http://dx.doi.org/10.3390/cancers11091299