The Link of the Prion Protein with Ca(2+) Metabolism and ROS Production, and the Possible Implication in Aβ Toxicity

The cellular prion protein (PrP(C)) is an ubiquitous cell surface protein mostly expressed in neurons, where it localizes to both pre- and post-synaptic membranes. PrP(C) aberrant conformers are the major components of mammalian prions, the infectious agents responsible for incurable neurodegenerati...

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Detalles Bibliográficos
Autores principales: De Mario, Agnese, Peggion, Caterina, Massimino, Maria Lina, Norante, Rosa Pia, Zulian, Alessandra, Bertoli, Alessandro, Sorgato, Maria Catia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770541/
https://www.ncbi.nlm.nih.gov/pubmed/31546771
http://dx.doi.org/10.3390/ijms20184640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770541/
https://www.ncbi.nlm.nih.gov/pubmed/31546771
http://dx.doi.org/10.3390/ijms20184640

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