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Discordant Effects of Putative Lysine Acetyltransferase Inhibitors in Biochemical and Living Systems
Lysine acetyltransferases (KATs) are exquisitely fine-tuned to target specific lysine residues on many proteins, including histones, with aberrant acetylation at distinct lysines implicated in different pathologies. However, researchers face a lack of molecular tools to probe the importance of site-...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770547/ https://www.ncbi.nlm.nih.gov/pubmed/31480793 http://dx.doi.org/10.3390/cells8091022 |