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Discordant Effects of Putative Lysine Acetyltransferase Inhibitors in Biochemical and Living Systems

Lysine acetyltransferases (KATs) are exquisitely fine-tuned to target specific lysine residues on many proteins, including histones, with aberrant acetylation at distinct lysines implicated in different pathologies. However, researchers face a lack of molecular tools to probe the importance of site-...

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Detalles Bibliográficos
Autores principales: Henry, Ryan A., Kuo, Yin-Ming, Siegel, Zarek S., Yen, Timothy J., Rhodes, Jennifer, Taylor, Erika A., Andrews, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770547/
https://www.ncbi.nlm.nih.gov/pubmed/31480793
http://dx.doi.org/10.3390/cells8091022