Downregulation of POFUT1 Impairs Secondary Myogenic Fusion Through a Reduced NFATc2/IL-4 Signaling Pathway

Past work has shown that the protein O-fucosyltransferase 1 (POFUT1) is involved in mammal myogenic differentiation program. Pofut1 knockdown (Po –) in murine C2C12 cells leads to numerous elongated and thin myotubes, suggesting significant defects in secondary fusion. Among the few pathways involve...

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Detalles Bibliográficos
Autores principales: Der Vartanian, Audrey, Chabanais, Julien, Carrion, Claire, Maftah, Abderrahman, Germot, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770550/
https://www.ncbi.nlm.nih.gov/pubmed/31500188
http://dx.doi.org/10.3390/ijms20184396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770550/
https://www.ncbi.nlm.nih.gov/pubmed/31500188
http://dx.doi.org/10.3390/ijms20184396

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