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Avian Expression Patterns and Genomic Mapping Implicate Leptin in Digestion and TNF in Immunity, Suggesting That Their Interacting Adipokine Role Has Been Acquired Only in Mammals

In mammals, leptin and tumor-necrosis factor (TNF) are prominent interacting adipokines mediating appetite control and insulin sensitivity. While TNF pleiotropically functions in immune defense and cell survival, leptin is largely confined to signaling energy stores in adipocytes. Knowledge about th...

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Detalles Bibliográficos
Autores principales: Seroussi, Eyal, Knytl, Martin, Pitel, Frédérique, Elleder, Daniel, Krylov, Vladimir, Leroux, Sophie, Morisson, Mireille, Yosefi, Sara, Miyara, Shoval, Ganesan, Saibaba, Ruzal, Mark, Andersson, Leif, Friedman-Einat, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770569/
https://www.ncbi.nlm.nih.gov/pubmed/31514326
http://dx.doi.org/10.3390/ijms20184489