Novel Carbazole-Piperazine Hybrid Small Molecule Induces Apoptosis by Targeting BCL-2 and Inhibits Tumor Progression in Lung Adenocarcinoma In Vitro and Xenograft Mice Model

Lung cancer is a type of deadly cancer and a leading cause of cancer associated death worldwide. BCL-2 protein is considered as an imperative target for the treatment of cancer due to their significant involvement in cell survival and death. A carbazole-piperazine hybrid molecule ECPU-0001 was desig...

Descripción completa

Detalles Bibliográficos
Autores principales: Mongre, Raj Kumar, Mishra, Chandra Bhushan, Prakash, Amresh, Jung, Samil, Lee, Beom Suk, Kumari, Shikha, Hong, Jin Tae, Lee, Myeong-Sok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770606/
https://www.ncbi.nlm.nih.gov/pubmed/31450709
http://dx.doi.org/10.3390/cancers11091245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770606/
https://www.ncbi.nlm.nih.gov/pubmed/31450709
http://dx.doi.org/10.3390/cancers11091245

Ejemplares similares