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High Concentration of C5a-Induced Mitochondria-Dependent Apoptosis in Murine Kidney Endothelial Cells

Patients with a relapse of idiopathic nephrotic syndrome have significantly increased levels of serum complement component 5a (C5a), and proteinuria has been noted in mice treated with C5a via changes in permeability of kidney endothelial cells (KECs) in established animal models. However, the apopt...

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Detalles Bibliográficos
Autores principales: Tsai, I-Jung, Lin, Wei-Chou, Yang, Yao-Hsu, Tseng, Yu-Lin, Lin, Yen-Hung, Chou, Chia-Hung, Tsau, Yong-Kwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770645/
https://www.ncbi.nlm.nih.gov/pubmed/31510052
http://dx.doi.org/10.3390/ijms20184465