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Blockade of the Adenosine A(3) Receptor Attenuates Caspase 1 Activation in Renal Tubule Epithelial Cells and Decreases Interleukins IL-1β and IL-18 in Diabetic Rats

Diabetic nephropathy (DN) is the main cause of end-stage renal disease, which remains incurable. The progression of DN is associated with progressive and irreversible renal fibrosis and also high levels of adenosine. Our aim was to evaluate the effects of ADORA3 antagonism on renal injury in strepto...

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Detalles Bibliográficos
Autores principales: Garrido, Wallys, Jara, Claudia, Torres, Angelo, Suarez, Raibel, Cappelli, Claudio, Oyarzún, Carlos, Quezada, Claudia, San Martín, Rody
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770662/
https://www.ncbi.nlm.nih.gov/pubmed/31540220
http://dx.doi.org/10.3390/ijms20184531