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Regulation of I(Ks) Potassium Current by Isoproterenol in Adult Cardiomyocytes Requires Type 9 Adenylyl Cyclase
The subunits KCNQ1 and KCNE1 generate the slowly activating, delayed rectifier potassium current, I(Ks), that responds to sympathetic stimulation and is critical for human cardiac repolarization. The A-kinase anchoring protein Yotiao facilitates macromolecular complex formation between I(Ks) and pro...
Autores principales: | Li, Yong, Hof, Thomas, Baldwin, Tanya A., Chen, Lei, Kass, Robert S., Dessauer, Carmen W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770663/ https://www.ncbi.nlm.nih.gov/pubmed/31461851 http://dx.doi.org/10.3390/cells8090981 |
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