Discovery of a Ruthenium Complex for the Theranosis of Glioma through Targeting the Mitochondrial DNA with Bioinformatic Methods

Glioma is the most aggressive and lethal brain tumor in humans. Mutations of mitochondrial DNA (mtDNA) are commonly found in tumor cells and are closely associated with tumorigenesis and progress. However, glioma-specific inhibitors that reflect the unique feature of tumor cells are rare. Here we un...

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Detalles Bibliográficos
Autores principales: Zhang, Le, Fu, Chen, Li, Jin, Zhao, Zizhen, Hou, Yixue, Zhou, Wei, Fu, Ailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770666/
https://www.ncbi.nlm.nih.gov/pubmed/31546801
http://dx.doi.org/10.3390/ijms20184643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770666/
https://www.ncbi.nlm.nih.gov/pubmed/31546801
http://dx.doi.org/10.3390/ijms20184643

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