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Detection of Androgen Receptor Variant 7 (ARV7) mRNA Levels in EpCAM-Enriched CTC Fractions for Monitoring Response to Androgen Targeting Therapies in Prostate Cancer

Expression of the androgen receptor splice variant 7 (ARV7) in circulating tumor cells (CTCs) has been associated with resistance towards novel androgen receptor (AR)-targeting therapies. While a multitude of ARV7 detection approaches have been developed, the simultaneous enumeration of CTCs and ass...

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Detalles Bibliográficos
Autores principales: Hille, Claudia, Gorges, Tobias M., Riethdorf, Sabine, Mazel, Martine, Steuber, Thomas, Von Amsberg, Gunhild, König, Frank, Peine, Sven, Alix-Panabières, Catherine, Pantel, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770695/
https://www.ncbi.nlm.nih.gov/pubmed/31514447
http://dx.doi.org/10.3390/cells8091067