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Fusaricidin-Type Compounds Create Pores in Mitochondrial and Plasma Membranes of Mammalian Cells

Fusaricidins and related LI-F compounds are effective bactericides and fungicides. Recently, we have found that they are highly toxic to mammalian cells. Here, we studied the effect of fusaricidin-type compounds (FTCs) on the membranes of mammalian cells. Ethanol extracts from Paenibacillus polymyxa...

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Detalles Bibliográficos
Autores principales: Mikkola, Raimo, Andersson, Maria, Kharechkina, Ekaterina, Kruglova, Svetlana, Kruglov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770722/
https://www.ncbi.nlm.nih.gov/pubmed/31480526
http://dx.doi.org/10.3390/biom9090433