CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients

Tamoxifen displays wide inter-individual variability (IIV) in its pharmacokinetics and treatment outcome. Data on tamoxifen pharmacokinetics and pharmacogenetics from black African breast cancer patient populations is lacking. We investigated the pharmacokinetic and pharmacogenetic profile of tamoxi...

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Detalles Bibliográficos
Autores principales: Ahmed, Jemal Hussien, Makonnen, Eyasu, Fotoohi, Alan, Aseffa, Abraham, Howe, Rawleigh, Aklillu, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770728/
https://www.ncbi.nlm.nih.gov/pubmed/31547390
http://dx.doi.org/10.3390/cancers11091353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770728/
https://www.ncbi.nlm.nih.gov/pubmed/31547390
http://dx.doi.org/10.3390/cancers11091353

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