Gene Co-Expression Networks Restructured Gene Fusion in Rhabdomyosarcoma Cancers

Rhabdomyosarcoma is subclassified by the presence or absence of a recurrent chromosome translocation that fuses the FOXO1 and PAX3 or PAX7 genes. The fusion protein (FOXO1-PAX3/7) retains both binding domains and becomes a novel and potent transcriptional regulator in rhabdomyosarcoma subtypes. Many...

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Detalles Bibliográficos
Autores principales: Helm, Bryan R., Zhan, Xiaohui, Pandya, Pankita H., Murray, Mary E., Pollok, Karen E., Renbarger, Jamie L., Ferguson, Michael J., Han, Zhi, Ni, Dong, Zhang, Jie, Huang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770752/
https://www.ncbi.nlm.nih.gov/pubmed/31480361
http://dx.doi.org/10.3390/genes10090665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770752/
https://www.ncbi.nlm.nih.gov/pubmed/31480361
http://dx.doi.org/10.3390/genes10090665

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