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Emerging Screening Approaches in the Development of Nrf2–Keap1 Protein–Protein Interaction Inhibitors

Due to role of the Keap1–Nrf2 protein–protein interaction (PPI) in protecting cells from oxidative stress, the development of small molecule inhibitors that inhibit this interaction has arisen as a viable approach to combat maladies caused by oxidative stress, such as cancers, neurodegenerative dise...

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Detalles Bibliográficos
Autores principales: Leung, Chung-Hang, Zhang, Jia-Tong, Yang, Guan-Jun, Liu, Hao, Han, Quan-Bin, Ma, Dik-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770765/
https://www.ncbi.nlm.nih.gov/pubmed/31509940
http://dx.doi.org/10.3390/ijms20184445