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Emerging Screening Approaches in the Development of Nrf2–Keap1 Protein–Protein Interaction Inhibitors
Due to role of the Keap1–Nrf2 protein–protein interaction (PPI) in protecting cells from oxidative stress, the development of small molecule inhibitors that inhibit this interaction has arisen as a viable approach to combat maladies caused by oxidative stress, such as cancers, neurodegenerative dise...
Autores principales: | Leung, Chung-Hang, Zhang, Jia-Tong, Yang, Guan-Jun, Liu, Hao, Han, Quan-Bin, Ma, Dik-Lung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770765/ https://www.ncbi.nlm.nih.gov/pubmed/31509940 http://dx.doi.org/10.3390/ijms20184445 |
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