A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions

Genetically-engineered mouse models (GEMMs) lacking diseased-associated gene(s) globally or in a tissue-specific manner represent an attractive tool with which to assess the efficacy and toxicity of targeted pharmacological inhibitors. Stat3 and Stat5a/b transcription factors have been implicated in...

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Detalles Bibliográficos
Autores principales: Moll, Herwig P., Mohrherr, Julian, Blaas, Leander, Musteanu, Monica, Stiedl, Patricia, Grabner, Beatrice, Zboray, Katalin, König, Margit, Stoiber, Dagmar, Rülicke, Thomas, Strehl, Sabine, Eferl, Robert, Casanova, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770775/
https://www.ncbi.nlm.nih.gov/pubmed/31443474
http://dx.doi.org/10.3390/cancers11091226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770775/
https://www.ncbi.nlm.nih.gov/pubmed/31443474
http://dx.doi.org/10.3390/cancers11091226

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