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TWIST1 Heterodimerization with E12 Requires Coordinated Protein Phosphorylation to Regulate Periostin Expression

Diffuse invasion into adjacent brain matter by glioblastoma (GBM) is largely responsible for their dismal prognosis. Previously, we showed that the TWIST1 (TW) bHLH transcription factor and its regulated gene periostin (POSTN) promote invasive phenotypes of GBM cells. Since TW functional effects are...

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Detalles Bibliográficos
Autores principales: Mikheeva, Svetlana A., Camp, Nathan D., Huang, Lei, Jain, Antrix, Jung, Sung Yun, Avci, Naze G., Tokita, Mari, Wolf-Yadlin, Alejandro, Zhang, Jing, Tapscott, Stephen J., Rostomily, Robert C., Mikheev, Andrei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770789/
https://www.ncbi.nlm.nih.gov/pubmed/31540485
http://dx.doi.org/10.3390/cancers11091392