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PKCδ Mediates NF-κB Inflammatory Response and Downregulates SIRT1 Expression in Liver Fibrosis

The precise mechanism of hepatic cirrhosis remains largely unclear. In particular, a potential regulatory mechanism by which protein kinase C-delta (PKCδ ) affects profibrogenic gene expression involved in hepatic cirrhosis has never been explored. In the present study, we investigated whether PKCδ...

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Detalles Bibliográficos
Autores principales: Lee, Su Jin, Kim, Su Ji, Lee, Hyun-Shik, Kwon, Oh-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770793/
https://www.ncbi.nlm.nih.gov/pubmed/31533364
http://dx.doi.org/10.3390/ijms20184607