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PKCδ Mediates NF-κB Inflammatory Response and Downregulates SIRT1 Expression in Liver Fibrosis
The precise mechanism of hepatic cirrhosis remains largely unclear. In particular, a potential regulatory mechanism by which protein kinase C-delta (PKCδ ) affects profibrogenic gene expression involved in hepatic cirrhosis has never been explored. In the present study, we investigated whether PKCδ...
Autores principales: | Lee, Su Jin, Kim, Su Ji, Lee, Hyun-Shik, Kwon, Oh-Shin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770793/ https://www.ncbi.nlm.nih.gov/pubmed/31533364 http://dx.doi.org/10.3390/ijms20184607 |
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