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Heteroplasmic Variants of Mitochondrial DNA in Atherosclerotic Lesions of Human Aortic Intima

Mitochondrial dysfunction and oxidative stress are likely involved in atherogenesis. Since the mitochondrial genome variation can alter functional activity of cells, it is necessary to assess the presence in atherosclerotic lesions of mitochondrial DNA (mtDNA) heteroplasmic mutations known to be ass...

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Detalles Bibliográficos
Autores principales: Sobenin, Igor A., Zhelankin, Andrey V., Khasanova, Zukhra B., Sinyov, Vasily V., Medvedeva, Lyudmila V., Sagaidak, Maria O., Makeev, Vsevolod J., Kolmychkova, Kira I., Smirnova, Anna S., Sukhorukov, Vasily N., Postnov, Anton Y., Grechko, Andrey V., Orekhov, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770808/
https://www.ncbi.nlm.nih.gov/pubmed/31500189
http://dx.doi.org/10.3390/biom9090455