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How Cells Handle DNA Breaks during Mitosis: Detection, Signaling, Repair, and Fate Choice

Mitosis is controlled by a complex series of signaling pathways but mitotic control following DNA damage remains poorly understood. Effective DNA damage sensing and repair is integral to survival but is largely thought to occur primarily in interphase and be repressed during mitosis due to the risk...

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Detalles Bibliográficos
Autores principales: Thompson, Ruth, Gatenby, Rachel, Sidi, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770852/
https://www.ncbi.nlm.nih.gov/pubmed/31500247
http://dx.doi.org/10.3390/cells8091049