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A Simple Method to Detect the Inhibition of Transcription Factor-DNA Binding Due to Protein–Protein Interactions In Vivo

Binding of transcription factors (TFs) to cis-regulatory elements (DNA) could modulate the expression of downstream genes, while interactions between TFs and other proteins might inhibit them binding to DNA. Nowadays, electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation (ChI...

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Detalles Bibliográficos
Autores principales: Yang, Guangzhe, Chao, Dong, Ming, Zhenhua, Xia, Jixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770856/
https://www.ncbi.nlm.nih.gov/pubmed/31500097
http://dx.doi.org/10.3390/genes10090684