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Catalase-Like Antioxidant Activity is Unaltered in Hypochlorous Acid Oxidized Horse Heart Myoglobin

Activated neutrophils release myeloperoxidase that produces the potent oxidant hypochlorous acid (HOCl). Exposure of the oxygen transport protein horse heart myoglobin (hhMb) to HOCl inhibits Iron III (Fe(III))-heme reduction by cytochrome b5 to oxygen-binding Iron II (Fe(II))Mb. Pathological concen...

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Detalles Bibliográficos
Autores principales: Ahmad, Gulfam, Chami, Belal, El Kazzi, Mary, Wang, Xiaosuo, Moreira, Maria Tereza S., Hamilton, Natasha, Maw, Aung Min, Hambly, Thomas W., Witting, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770884/
https://www.ncbi.nlm.nih.gov/pubmed/31540488
http://dx.doi.org/10.3390/antiox8090414