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Catalase-Like Antioxidant Activity is Unaltered in Hypochlorous Acid Oxidized Horse Heart Myoglobin
Activated neutrophils release myeloperoxidase that produces the potent oxidant hypochlorous acid (HOCl). Exposure of the oxygen transport protein horse heart myoglobin (hhMb) to HOCl inhibits Iron III (Fe(III))-heme reduction by cytochrome b5 to oxygen-binding Iron II (Fe(II))Mb. Pathological concen...
Autores principales: | Ahmad, Gulfam, Chami, Belal, El Kazzi, Mary, Wang, Xiaosuo, Moreira, Maria Tereza S., Hamilton, Natasha, Maw, Aung Min, Hambly, Thomas W., Witting, Paul K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770884/ https://www.ncbi.nlm.nih.gov/pubmed/31540488 http://dx.doi.org/10.3390/antiox8090414 |
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