γ-H2AX Foci Persistence at Chromosome Break Suggests Slow and Faithful Repair Phases Restoring Chromosome Integrity

Many toxic agents can cause DNA double strand breaks (DSBs), which are in most cases quickly repaired by the cellular machinery. Using ionising radiation, we explored the kinetics of DNA lesion signaling and structural chromosome aberration formation at the intra- and inter-chromosomal level. Using...

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Detalles Bibliográficos
Autores principales: Ricoul, Michelle, Gnana Sekaran, Tamizh Selvan, Brochard, Patricia, Herate, Cecile, Sabatier, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770925/
https://www.ncbi.nlm.nih.gov/pubmed/31546867
http://dx.doi.org/10.3390/cancers11091397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770925/
https://www.ncbi.nlm.nih.gov/pubmed/31546867
http://dx.doi.org/10.3390/cancers11091397

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