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Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis

Two novel molecular mechanisms with a driver role in pituitary tumorigenesis have been recently identified. They are (a) mutations in the Ubiquitin-Specific Protease 8 (USP8) gene in corticotroph tumors and (b) overexpression of the HMGA1 and HMGA2 genes in most of the pituitary tumors. Moreover, de...

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Detalles Bibliográficos
Autores principales: D’Angelo, Daniela, De Martino, Marco, Arra, Claudio, Fusco, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770943/
https://www.ncbi.nlm.nih.gov/pubmed/31487906
http://dx.doi.org/10.3390/cancers11091302