The miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas

Defective DNA damage response (DDR) is frequently associated with tumorigenesis. Abrogation of DDR leads to genomic instability, which is one of the most common characteristics of human cancers. TP53 mutations with gain-of-function activity are associated with tumors under high replicative stress, h...

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Detalles Bibliográficos
Autores principales: Valenti, Fabio, Sacconi, Andrea, Ganci, Federica, Grasso, Giuseppe, Strano, Sabrina, Blandino, Giovanni, Di Agostino, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771082/
https://www.ncbi.nlm.nih.gov/pubmed/31514456
http://dx.doi.org/10.3390/cancers11091347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771082/
https://www.ncbi.nlm.nih.gov/pubmed/31514456
http://dx.doi.org/10.3390/cancers11091347

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