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Extracellular and macropinocytosis internalized ATP work together to induce epithelial–mesenchymal transition and other early metastatic activities in lung cancer

BACKGROUND: Extracellular ATP (eATP) was shown to induce epithelial–mesenchymal transition (EMT), a very important early process in metastasis, in cancer cells via purinergic receptor signaling. However, the exact induction mechanisms are far from fully known. We previously described that eATP is in...

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Detalles Bibliográficos
Autores principales: Cao, Yanyang, Wang, Xuan, Li, Yunsheng, Evers, Maria, Zhang, Haiyun, Chen, Xiaozhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771108/
https://www.ncbi.nlm.nih.gov/pubmed/31582910
http://dx.doi.org/10.1186/s12935-019-0973-0