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Tumor‐Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma

CD73, a cell‐surface N‐linked glycoprotein that produces extracellular adenosine, is a novel target for cancer immunotherapy. Although anti‐CD73 antibodies have entered clinical development, CD73 has both protumor and antitumor functions, depending on the target cell and tumor type. The aim of this...

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Detalles Bibliográficos
Autores principales: Alcedo, Karel P., Guerrero, Andres, Basrur, Venkatesha, Fu, Dong, Richardson, Monea L., McLane, Joshua S., Tsou, Chih‐Chiang, Nesvizhskii, Alexey I., Welling, Theodore H., Lebrilla, Carlito B., Otey, Carol A., Kim, Hong Jin, Omary, M. Bishr, Snider, Natasha T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771166/
https://www.ncbi.nlm.nih.gov/pubmed/31592495
http://dx.doi.org/10.1002/hep4.1410