Cargando…
Tumor‐Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma
CD73, a cell‐surface N‐linked glycoprotein that produces extracellular adenosine, is a novel target for cancer immunotherapy. Although anti‐CD73 antibodies have entered clinical development, CD73 has both protumor and antitumor functions, depending on the target cell and tumor type. The aim of this...
Autores principales: | Alcedo, Karel P., Guerrero, Andres, Basrur, Venkatesha, Fu, Dong, Richardson, Monea L., McLane, Joshua S., Tsou, Chih‐Chiang, Nesvizhskii, Alexey I., Welling, Theodore H., Lebrilla, Carlito B., Otey, Carol A., Kim, Hong Jin, Omary, M. Bishr, Snider, Natasha T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771166/ https://www.ncbi.nlm.nih.gov/pubmed/31592495 http://dx.doi.org/10.1002/hep4.1410 |
Ejemplares similares
-
Alternative splicing of human NT5E in cirrhosis and hepatocellular carcinoma produces a negative regulator of ecto-5′-nucleotidase (CD73)
por: Snider, Natasha T., et al.
Publicado: (2014) -
Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells
por: Maitra, Dhiman, et al.
Publicado: (2019) -
The sweet side of vimentin
por: Snider, Natasha T, et al.
Publicado: (2018) -
CD73 Maintains Hepatocyte Metabolic Integrity and Mouse Liver Homeostasis in a Sex-Dependent Manner
por: Alcedo, Karel P., et al.
Publicado: (2021) -
In-Depth Method for the Characterization of Glycosylation
in Manufactured Recombinant Monoclonal Antibody Drugs
por: Song, Ting, et al.
Publicado: (2014)