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Cooperativity of co-factor NR2F2 with Pioneer Factors GATA3, FOXA1 in promoting ERα function

Estrogen receptor α (ERα) drives growth in the majority of human breast cancers by binding to regulatory elements and inducing transcriptional events that promote tumor growth. ERα binding activity largely depends on access to binding sites on chromatin, which is facilitated in part by Pioneer Facto...

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Detalles Bibliográficos
Autores principales: Jiang, Guojuan, Wang, Xinrui, Sheng, Dandan, Zhou, Lei, Liu, Yang, Xu, Congling, Liu, Suling, Zhang, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771234/
https://www.ncbi.nlm.nih.gov/pubmed/31588232
http://dx.doi.org/10.7150/thno.34874