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Transport and Biotransformation of Gliclazide and the Effect of Deoxycholic Acid in a Probiotic Bacteria Model

Introduction: Inter-individual differences in gut microflora composition may affect drug metabolism and overall therapeutic response. Gliclazide is a drug characterized by large inter-individual differences in therapeutic response; however, the causes of these differences are not fully explained and...

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Detalles Bibliográficos
Autores principales: Ðanić, Maja, Stanimirov, Bojan, Pavlović, Nebojša, Vukmirović, Saša, Lazić, Jelena, Al-Salami, Hani, Mikov, Momir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771299/
https://www.ncbi.nlm.nih.gov/pubmed/31607925
http://dx.doi.org/10.3389/fphar.2019.01083