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Renoprotective effect of irbesartan in a rat model of gentamicin-induced nephrotoxicity: Role of oxidative stress

BACKGROUND: The renin–angiotensin system (RAS) is essential in renal physiology; however, disturbance of the RAS is one of the chief pathways involved in renal injury. Dysregulation of RAS may result in both glomerular and tubulointerstitial injuries through direct effects of angiotensin II (Ang II)...

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Detalles Bibliográficos
Autores principales: Al-Kuraishy, Hayder M., Al-Gareeb, Ali I., Al-Naimi, Marwa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771317/
https://www.ncbi.nlm.nih.gov/pubmed/31579224
http://dx.doi.org/10.4103/JLP.JLP_136_18