An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion

Rapid perturbation of protein function permits the ability to define primary molecular responses while avoiding downstream cumulative effects of protein dysregulation. The auxin-inducible degron (AID) system was developed as a tool to achieve rapid and inducible protein degradation in nonplant syste...

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Detalles Bibliográficos
Autores principales: Sathyan, Kizhakke Mattada, McKenna, Brian D., Anderson, Warren D., Duarte, Fabiana M., Core, Leighton, Guertin, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Resource/Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771385/
https://www.ncbi.nlm.nih.gov/pubmed/31467088
http://dx.doi.org/10.1101/gad.328237.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771385/
https://www.ncbi.nlm.nih.gov/pubmed/31467088
http://dx.doi.org/10.1101/gad.328237.119

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