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An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion
Rapid perturbation of protein function permits the ability to define primary molecular responses while avoiding downstream cumulative effects of protein dysregulation. The auxin-inducible degron (AID) system was developed as a tool to achieve rapid and inducible protein degradation in nonplant syste...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771385/ https://www.ncbi.nlm.nih.gov/pubmed/31467088 http://dx.doi.org/10.1101/gad.328237.119 |