Regulation of histone methylation by automethylation of PRC2

Polycomb-repressive complex 2 (PRC2) is a histone methyltransferase that is critical for regulating transcriptional repression in mammals. Its catalytic subunit, EZH2, is responsible for the trimethylation of H3K27 and also undergoes automethylation. Using mass spectrometry analysis of recombinant h...

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Detalles Bibliográficos
Autores principales: Wang, Xueyin, Long, Yicheng, Paucek, Richard D., Gooding, Anne R., Lee, Thomas, Burdorf, Rachel M., Cech, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771386/
https://www.ncbi.nlm.nih.gov/pubmed/31488576
http://dx.doi.org/10.1101/gad.328849.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771386/
https://www.ncbi.nlm.nih.gov/pubmed/31488576
http://dx.doi.org/10.1101/gad.328849.119

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