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Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming

Induction and reversal of chromatin silencing is critical for successful development, tissue homeostasis, and the derivation of induced pluripotent stem cells (iPSCs). X-Chromosome inactivation (XCI) and reactivation (XCR) in female cells represent chromosome-wide transitions between active and inac...

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Detalles Bibliográficos
Autores principales: Janiszewski, Adrian, Talon, Irene, Chappell, Joel, Collombet, Samuel, Song, Juan, De Geest, Natalie, To, San Kit, Bervoets, Greet, Marin-Bejar, Oskar, Provenzano, Caterina, Vanheer, Lotte, Marine, Jean-Christophe, Rambow, Florian, Pasque, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771397/
https://www.ncbi.nlm.nih.gov/pubmed/31515287
http://dx.doi.org/10.1101/gr.249706.119