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Identifying clusters of cis-regulatory elements underpinning TAD structures and lineage-specific regulatory networks

Cellular identity relies on cell-type–specific gene expression controlled at the transcriptional level by cis-regulatory elements (CREs). CREs are unevenly distributed across the genome, giving rise to individual CREs and clusters of CREs (COREs). Technical and biological features hinder CORE identi...

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Detalles Bibliográficos
Autores principales: Madani Tonekaboni, Seyed Ali, Mazrooei, Parisa, Kofia, Victor, Haibe-Kains, Benjamin, Lupien, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771399/
https://www.ncbi.nlm.nih.gov/pubmed/31533978
http://dx.doi.org/10.1101/gr.248658.119