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Identifying clusters of cis-regulatory elements underpinning TAD structures and lineage-specific regulatory networks
Cellular identity relies on cell-type–specific gene expression controlled at the transcriptional level by cis-regulatory elements (CREs). CREs are unevenly distributed across the genome, giving rise to individual CREs and clusters of CREs (COREs). Technical and biological features hinder CORE identi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771399/ https://www.ncbi.nlm.nih.gov/pubmed/31533978 http://dx.doi.org/10.1101/gr.248658.119 |