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RNA components of the spliceosome regulate tissue- and cancer-specific alternative splicing

Alternative splicing of pre-mRNAs plays a pivotal role during the establishment and maintenance of human cell types. Characterizing the trans-acting regulatory proteins that control alternative splicing has therefore been the focus of much research. Recent work has established that even core protein...

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Detalles Bibliográficos
Autores principales: Dvinge, Heidi, Guenthoer, Jamie, Porter, Peggy L., Bradley, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771400/
https://www.ncbi.nlm.nih.gov/pubmed/31434678
http://dx.doi.org/10.1101/gr.246678.118