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Hyaluronan activated-metabolism phenotype (HAMP) in pancreatic ductal adenocarcinoma

Background: The aggressiveness of pancreatic ductal adenocarcinoma (PDAC) is enhanced by its interactions with stromal extracellular matrix, notably with hyaluronan (HA). Our previous studies have demonstrated increased expression of genes involved in HA synthesis and degradation in PDAC, suggesting...

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Detalles Bibliográficos
Autores principales: Kudo, Yuzan, Kohi, Shiro, Hirata, Keiji, Goggins, Michael, Sato, Norihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771457/
https://www.ncbi.nlm.nih.gov/pubmed/31608136
http://dx.doi.org/10.18632/oncotarget.27172