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Impact of exosomal HIV-1 Tat expression on the human cellular proteome

HIV-1 exists in a latent form in all infected patients. When antiretroviral therapy is stopped, viral replication resumes. The HIV-1 Tat protein is a potent activator of viral transcription. Our previous work has demonstrated that exosomal formulations of Tat can reverse HIV-1 latency in primary CD4...

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Detalles Bibliográficos
Autores principales: Lu, Huafei, Tang, Xiaoli, Sibley, Mitchell, Coburn, Jillian, Rao, R. Shyama Prasad, Ahsan, Nagib, Ramratnam, Bharat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771461/
https://www.ncbi.nlm.nih.gov/pubmed/31608139
http://dx.doi.org/10.18632/oncotarget.27207