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Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma

Neuroblastoma remains one of the most difficult pediatric solid tumors to treat. In particular, the refractory and relapsing neuroblastomas are highly heterogeneous with diverse molecular profiles. We previously demonstrated that AKT2 plays critical roles in the regulation of neuroblastoma tumorigen...

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Detalles Bibliográficos
Autores principales: Kim, Kwang Woon, Kim, Julia Y., Qiao, Jingbo, Clark, Rachael A., Powers, Camille M., Correa, Hernan, Chung, Dai H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771463/
https://www.ncbi.nlm.nih.gov/pubmed/31608140
http://dx.doi.org/10.18632/oncotarget.27210